GENERAL CATALOGUE
S-Methyl-N,N-diethylthiolcarbamate
HY-151229 · 25 mg
MedChemExpress · Cat: HY-151229
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Catalog No: HY-151229
CAS No: 686-07-7
Category: Metabolic Enzyme Protease
Pack Size: 25 mg
Brand: MedChemExpress
Description
S-Methyl-N,N-diethylthiolcarbamate DETC-Me; DDTC-Me is the active metabolite of the aldehyde dehydrogenase inhibitor disulfiram HY-B0240 . It is produced by the methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. S-Methyl-N,N-diethylthiolcarbamate DETC-Me; DDTC-Me inhibits rat liver low Km aldehyde dehydrogenase ALDH ID50=15.5 mg/kg . When administered at a dose of 20.6 mg/kg, it decreases mean arterial pressure MAP and increases heart rate in rats during ethanol stimulation.
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