GENERAL CATALOGUE
(S,R,S)-MI-1061
HY-125858B · 50 mg
MedChemExpress · Cat: HY-125858B
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medchemexpress.com/s-r-s-mi-1061.htmlCatalog No: HY-125858B
CAS No: 1410738-90-7
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress
Description
S,R,S -MI-1061 is the isomer of MI-1061 HY-125858 . S,R,S -MI-1061 can used to synthesize Antibody-Drug Conjugates ADCs . MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 MDM2-p53 interaction inhibitor IC50=4.4 nM; Ki=0.16 nM . MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.
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