GENERAL CATALOGUE
(S)-TNG260
HY-153358A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-153358A
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medchemexpress.com/s-tng260.htmlCatalog No: HY-153358A
CAS No: 2935964-93-3
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
S -TNG260 is an isomer of TNG260 HY-153358 . TNG260 is a CoREST selective deacetylase CoreDAC inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3. TNG260 causes HDAC1 inhibition and reverses anti-PD1 resistance driven by STK11 deletion. TNG260 reduces intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killing.
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