GENERAL CATALOGUE
(S)-VU0637120
HY-165125 · 1 mg
MedChemExpress · Cat: HY-165125
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medchemexpress.com/s-vu0637120.htmlCatalog No: HY-165125
CAS No: 1175940-86-9
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
S -VU0637120 is a Y4R antagonist that effectively reduces the binding response of its endogenous ligand, pancreatic polypeptide PP , on Y4R, with an IC50 value of 2.7 ?M. S -VU0637120 binds to the allosteric site of Y4R, which is located in the core region of the Y4R transmembrane structure, near the binding pocket of pancreatic polypeptide PP , with a KB value of 300-400 nM. S -VU0637120 holds potential for research in the field of metabolic diseases.
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