GENERAL CATALOGUE
S07-2010
HY-150644 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-150644
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Catalog No: HY-150644
CAS No: 1223194-71-5
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
S07-2010 is a potent pan-AKR1C aldo-keto reductase family 1 member C inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 ?M for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells.
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