

HY-176533 · 5 mg
MedChemExpress · Cat: HY-176533
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medchemexpress.com/s1pr5-in-1.htmlDescription
S1PR5-IN-1 Compound 7a is a selective and BBB-penetrable S1PR5 inhibitor with an IC50 of 85.4 nM. S1PR5-IN-1 has a superior binding capacity on S1PR5 with Kds of 2.2, 4.6, and 27.6 nM for recombinant human S1PR5 cell membranes, C57BL/6 mouse brain, and human cerebral cortex, respectively. S1PR5-IN-1 can be used for neurodegenerative disorders like multiple sclerosis research.







