GENERAL CATALOGUE
Safusidenib
HY-145594 · 5 mg
MedChemExpress · Cat: HY-145594
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medchemexpress.com/safusidenib.htmlCatalog No: HY-145594
CAS No: 1898206-17-1
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
Safusidenib AB-291; DS-1001 is an orally bioavailable, selective mutant IDH1 inhibitor. Safusidenib strongly inhibits mutant IDH1 but not wild-type IDH1. Safusidenib impairs tumor activity in chondrosarcoma. Safusidenib exhibits activity against IDH1R132H, and IDH1R132C with IC50s of 15, and 130 nM in assays without any preincubation, respectively.
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