GENERAL CATALOGUE
SAH-SOS1A
HY-P2265 · 50 mg
MedChemExpress · Cat: HY-P2265
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/sah-sos1a.html
Sponsored
Catalog No: HY-P2265
CAS No: 1652561-87-9
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
SAH-SOS1A is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A binds to wild-type and mutant KRAS G12D, G12V, G12C, G12S, and Q61H with nanomolar affinity EC50=106-175 nM , directly and independently blocks nucleotide association, impairs KRAS-driven cancer cell viability, and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS.
More from MedChemExpress
GPR120 Agonist 1
HY-108711
GPCR G Protein
AG-045572
HY-107534
GPCR G Protein
Pamabrom
HY-17391
GPCR G Protein
ZD-7114
HY-101320
GPCR G Protein
Vasopressin Dimer (anti-parallel) (TFA)
HY-P5214
GPCR G Protein
Zimeldine-d6
HY-118835S
GPCR G Protein
ZM241385 (Standard)
HY-19532R
GPCR G Protein
(5S,6S)-DiHETE
HY-130138
GPCR G Protein