

HY-170431 · 50 mg
MedChemExpress · Cat: HY-170431
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medchemexpress.com/sal-0010042.htmlDescription
SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase ? PDE? , that inhibits the hydrolysis of cAMP and cGMP IC50=48.9 nM in gametocytes, activates PKG, and inhibits the growth and development of Plasmodium IC50 for 3D7 and Dd2 is 142 nM and 218 nM . SAL-0010042 inhibits hPDE5 and hPDE6 with IC50 of 632 nM and 73 nM.







