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SAL-0010042
GENERAL CATALOGUE

SAL-0010042

HY-170431 · 50 mg

MedChemExpress · Cat: HY-170431

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medchemexpress.com/sal-0010042.html
Catalog No: HY-170431
CAS No: 521298-46-4
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

SAL-0010042 is the inhibitor for Plasmodium phosphodiesterase ? PDE? , that inhibits the hydrolysis of cAMP and cGMP IC50=48.9 nM in gametocytes, activates PKG, and inhibits the growth and development of Plasmodium IC50 for 3D7 and Dd2 is 142 nM and 218 nM . SAL-0010042 inhibits hPDE5 and hPDE6 with IC50 of 632 nM and 73 nM.

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