GENERAL CATALOGUE
Samuraciclib hydrochloride hydrate
HY-103712C · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103712C
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medchemexpress.com/samuraciclib-hydrochloride-hydrate.htmlCatalog No: HY-103712C
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Samuraciclib CT7001 hydrochloride hydrate is a potent, selective, ATP-competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride hydrate displays 45-, 15-, 230- and 30-fold selectivity over CDK1, CDK2 IC50 of 578 nM , CDK5 and CDK9, respectively. Samuraciclib hydrochloride hydrate inhibits the growth of breast cancer cell lines with GI50 values between 0.2-0.3 ?M. Samuraciclib hydrochloride hydrate has anti-tumor effects.
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