GENERAL CATALOGUE
Sappanone A
HY-113556 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-113556
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Catalog No: HY-113556
CAS No: 102067-84-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Sappanone A is an orally active homoisoflavone found in sappan L. Sappanone A is a PDE4 and NF-?B inhibitor with anti-inflammatory and antioxidant effect. Sappanone A induces HO-1 expression through activation of Nrf2 pathway. Sappanone A also inhibits RANKL-induced osteoclastogenesis. Sappanone A has great potential in the research of inflammation-related and cardiovascular .