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SARS-CoV-2-IN-60
GENERAL CATALOGUE

SARS-CoV-2-IN-60

HY-155280 · 50 mg

MedChemExpress · Cat: HY-155280

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Catalog No: HY-155280
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

SARS-CoV-2-IN-60 compound 5a is an S-adenosylmethionine SAM -competitive and irreversible SARS-CoV-2 nsp16-nsp10 methyltransferase activity inhibitor with an IC50 of 9 ?M and a Ki of 26 ?M. SARS-CoV-2-IN-60 can specifically occupy a newly identified pocket adjacent to the SAM-binding site on nsp16. SARS-CoV-2-IN-60 has the potential for pan-coronavirus therapeutics.

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