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SARS-CoV-2-IN-81
GENERAL CATALOGUE

SARS-CoV-2-IN-81

HY-161261 · 50 mg

MedChemExpress · Cat: HY-161261

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Catalog No: HY-161261
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

SARS-CoV-2-IN-81 compound 12e is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection.

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