SARS-CoV-2 Mpro-IN-43

Description

SARS-CoV-2 Mpro-IN-43 Compound 1 is a coronavirus main protease Mpro inhibitor IC50: 72 ?M . SARS-CoV-2 Mpro-IN-43 interacts with key residues in the active site of Mpro via non-covalent binding, exerting its anti-coronavirus effect. SARS-CoV-2 Mpro-IN-43 exhibits moderate to low cytotoxicity, with CC50 values of 13.24, 41.02, and 42.26 AAasAasAAmuM in HaCaT, HEK293T, and HepG2 cells, respectively. SARS-CoV-2 Mpro-IN-43 can be used in anti-SARS-CoV-2 research.