GENERAL CATALOGUE
SB 242084 dihydrochloride
HY-13409A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13409A
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Manufacturer product page
medchemexpress.com/SB-242084-hydrochloride.htmlCatalog No: HY-13409A
CAS No: 1049747-87-6
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SB 242084 dihydrochloride is a selective, competitive and high-affinity pKi=9.0 5-HT2C receptor antagonist crosses the blood-brain barrier . SB 242084 dihydrochloride increases basal activity of dopaminergic neurons in the ventral tegmental area VTA of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 dihydrochloride also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 dihydrochloride has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage.