GENERAL CATALOGUE
SB-284851-BT
HY-136794 · 50 mg
MedChemExpress · Cat: HY-136794
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Manufacturer product page
medchemexpress.com/sb-284851-bt.htmlCatalog No: HY-136794
CAS No: 219769-23-0
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
SB-284851-BT is an inhibitor of BRD4/p38?/BRDT. SB-284851-BT inhibits BRD4-BD1 IC50=1.7 AAasAasAAmuM , p38? Kd=0.47 nM , BRDT 1 IC50=18 AAasAasAAmuM and BRD4 1 IC50=3.7 AAasAasAAmuM . SB-284851-BT reduces IL-8 production by inhibiting p38?, as well as inhibiting BRD4 to down-regulates c-Myc and NF-?B gene pathways in cancer. SB-284851-BT can combined with the bromine domain and extra terminal BET .
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