GENERAL CATALOGUE
SB-328437
HY-103363 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103363
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medchemexpress.com/sb-328437.htmlCatalog No: HY-103363
CAS No: 247580-43-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM. SB-328437 can inhibit eosinophil migration induced by eotaxin, eotaxin-2, and monocyte chemotactic protein-4. In addition, SB-328437 can sensitize 5-FU HY-90006 -resistant gastric cancer cells. SB-328437 can also reduce the recruitment of neutrophils to the lungs and pulmonary inflammation during acute inflammation. SB-328437 can be used in the research of inflammation-related diseases.
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