GENERAL CATALOGUE
SB-334867 free base
HY-10895A · 5 mg
MedChemExpress · Cat: HY-10895A
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Manufacturer product page
medchemexpress.com/SB-334867-free-base.htmlCatalog No: HY-10895A
CAS No: 792173-99-0
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
SB-334867 free base SB334867A free base is an excellent, selective and bloodAAasAasAabrain barrier permeable orexin-1 OX1 receptor antagonist, shows selectivity over OX2 pKb=7.4 , 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.
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