GENERAL CATALOGUE
SB-334867
HY-10895 · 10 mM * 1 mL in Water
MedChemExpress · Cat: HY-10895
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medchemexpress.com/sb-334867.htmlCatalog No: HY-10895
CAS No: 249889-64-3
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress
Description
SB-334867 SB 334867A is an excellent,selective and blood-brain barrier permeable orexin-1 OX1 receptor antagonist, shows selectivity over OX2 pKb=7.4 , 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.
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