SB-334867 (Standard)

Description

SB-334867 Standard is the analytical standard of SB-334867. This product is intended for research and analytical applications. SB-334867 SB 334867A is an excellent,selective and blood-brain barrier permeable orexin-1 OX1 receptor antagonist, shows selectivity over OX2 pKb=7.4 , 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.