GENERAL CATALOGUE
SB-772077B dihydrochloride
HY-108518 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-108518
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Manufacturer product page
medchemexpress.com/sb-772077b-dihydrochloride.htmlCatalog No: HY-108518
CAS No: 607373-46-6
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
SB-772077B dihydrochloride is an orally active aminofuran-based Rho kinase ROCK inhibitor with IC50 values of 5.6 nM and 6 nM for ROCK1 and ROCK2, respectively. SB-772077B dihydrochloride reduces inflammatory cytokines TNF-? and IL-6 . SB-772077B dihydrochloride relaxes aortic rings and lowers blood pressure. SB-772077B dihydrochloride can be used in the research of inflammatory diseases.