GENERAL CATALOGUE
SBI-477
HY-124418 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124418
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Catalog No: HY-124418
CAS No: 781628-99-7
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SBI-477 is a chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA. SBI-477 can lead to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein TXNIP and arrestin domain-containing 4 ARRDC4 . SBI-477 coordinately inhibits triacylglyceride TAG synthesis and enhances basal glucose uptake in human skeletal myocytes.
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