

HY-126255 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-126255
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medchemexpress.com/sbi-797812.htmlDescription
SBI-797812 is an orally active nicotinamide phosphoribosyltransferase NAMPT activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD+. SBI-797812 increases intracellular nicotinamide mononucleotide NMN and elevates liver NAD+ in mice.







