GENERAL CATALOGUE
SBI-810 hydrochloride
HY-164795A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-164795A
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Catalog No: HY-164795A
CAS No: 2772746-58-2
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SBI-810 hydrochloride is a functionally selected ?-arrestin-biased neurotensin receptor 1 NTSR1 allosteric modulator. SBI-810 hydrochloride modulates NTSR1 G protein signaling in a G protein-specific manner in the presence of the endogenous ligand, neurotensin NT . SBI-810 hydrochloride fully antagonizes NT-induced activation of Gq, partially antagonizes NT-induced activation of Gi1 and is permissive of NTSR1 activation of GoA and G12.
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