GENERAL CATALOGUE
SC144 hydrochloride
HY-15614A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15614A
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/SC144-hydrochloride.htmlCatalog No: HY-15614A
CAS No: 917497-70-2
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
SC144 hydrochloride is a first-in-class, orally active gp130 IL6-beta inhibitor. SC144 hydrochloride binds gp130, induces gp130 phosphorylation S782 and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 hydrochloride shows potent inhibition of gp130 ligand-triggered signaling. SC144 hydrochloride induces apoptosis in human ovarian cancer cells.
More from MedChemExpress
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HY-170379
Apoptosis