GENERAL CATALOGUE
SCH-23390 hydrochloride
HY-19545A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-19545A
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medchemexpress.com/SCH_23390_hydrochloride.htmlCatalog No: HY-19545A
CAS No: 125941-87-9
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SCH-23390 hydrochloride R- + -SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium GIRK channels with an IC50 of 268 nM.
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