GENERAL CATALOGUE
SCH-900875
HY-165428 · 1 mg
MedChemExpress · Cat: HY-165428
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medchemexpress.com/sch-900875.htmlCatalog No: HY-165428
CAS No: 907206-98-8
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
SCH-900875 is an orally active, brain-penetrant and selective CXCR3 receptor inhibitor, which also shows high selectivity over CXCR1 and CXCR2 receptors. SCH-900875 binds to CXCR3, blocking the binding of ligands CXCL9, CXCL10, and CXCL11, inhibiting downstream G protein and ?-arrestin signaling pathways to suppress inflammatory cell migration. SCH-900875 is promising for research of autoimmune diseases rheumatoid arthritis, multiple sclerosis and inflammatory disorders psoriasis, inflammatory bowel disease .
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