GENERAL CATALOGUE
SCH529074
HY-110088 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-110088
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Manufacturer product page
medchemexpress.com/sch529074.htmlCatalog No: HY-110088
CAS No: 922150-11-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD DNA binding domain with a Ki of 1-2 ?M in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma NSCLC .
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