GENERAL CATALOGUE
SD-436
HY-169360 · 1 mg
MedChemExpress · Cat: HY-169360
₹950 – ₹1,450 approx.This price excludes freight and taxes. Please RFQ to get the final price.
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/sd-436.html
Sponsored
Catalog No: HY-169360
CAS No: 2497585-50-7
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress
Description
SD-436 is a highly selective and efficacious STAT3 PROTAC degrader DC50: 0.5 ?M , with IC50 of 19 nM STAT3 , 270 nM STAT1 , 360 nM STAT4 , >10 ?M STAT5 and >10 ?M STAT6 . SD-436 promotes ubiquitination and degradation of STAT3, and induces tumor regression. SD-436 can be used for tumor research, such as leukemia and lymphoma Pink: STAT3 ligand HY-169361 ; Blue: E3 ligase ligand HY-43722 ; Black: linker HY-147052 .
More from MedChemExpress
STAT6-IN-2
HY-153991
JAK STAT Signaling
EGFR-IN-115
HY-162602
JAK STAT Signaling
ErbB-2-binding peptide
HY-P4082
JAK STAT Signaling
TX2-121-1
HY-118998
JAK STAT Signaling
AZ7550
HY-B0794
JAK STAT Signaling
EGFR-IN-38
HY-144055
JAK STAT Signaling
CCT365623 hydrochloride
HY-124674A
JAK STAT Signaling
HER2-IN-20
HY-163657
JAK STAT Signaling