SDH-IN-24

Description

SDH-IN-24 Compound 51 is an inhibitor of succinate dehydrogenase SDH . The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus B. xylophilus is 6.9 mg/L, and the IC50 for SDH is 15.0 ?M. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields.