SDHB Mouse Monoclonal Antibody

Description

EnkiLife offers the SDHB Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ELISA,FC application. Alternative Names of Immunogen: IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.