GENERAL CATALOGUE
Se2h
HY-159915 · 50 mg
MedChemExpress · Cat: HY-159915
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Catalog No: HY-159915
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Se2h is a cruzain inhibitor that exhibits strong activity against the intracellular amastigotes of Trypanosoma cruzi EC50 1 ?M, SI 10 , with an inhibitory activity against cruzain of IC50 100 nM SI 5.55 . Compared to Benznidazole HY-B1548 and the cruzain inhibitor K777 HY-119293 , Se2h shows superior selectivity and inhibition, while its selenazole structure reduces selenium-related toxicity. Se2h exhibits antiparasitic activity and holds promise for research in Chagas disease.
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