SEC61B Rabbit Polyclonal Antibody

Description

EnkiLife offers the SEC61B Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for IHC,ELISA application. Alternative Names of Immunogen: Protein transport protein Sec61 subunit beta. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:50-1:200,ELISA 1:5000-1:20000 Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],function:Necessary for protein translocation in the endoplasmic reticulum.,similarity:Belongs to the SEC61-beta family.,subunit:Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma. Part of a complex composed of SEC61, SEC62 and SEC63. Interacts with SEC62.,