GENERAL CATALOGUE
Seladelpar Lysine dihydrate
HY-19522C · 5 mg
MedChemExpress · Cat: HY-19522C
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Catalog No: HY-19522C
CAS No: 928821-40-3
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
Seladelpar MBX-8025 Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar HY-19522 . Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-?, with EC50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPAR? and PPAR? receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model.
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