GENERAL CATALOGUE
Selvigaltin
HY-147041 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-147041
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medchemexpress.com/selvigaltin.htmlCatalog No: HY-147041
CAS No: 1978336-95-6
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Selvigaltin GB1211 is an orally active galectin-3 small molecule inhibitor with an IC50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function AST, ALT, bilirubin , inflammation cells foci and fibrosis PSR, SHG , as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers IL6, TGF?3, SNAI2, collagen . Selvigaltin restores T-cell activity and induces less tumors and metastasis.
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