GENERAL CATALOGUE
SEN177
HY-136780 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136780
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Catalog No: HY-136780
CAS No: 2117405-13-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SEN177 is an orally effect glutamine cyclase QC inhibitor. The Ki of SEN177 for human glutamine cyclase hQC is 20 nM, and the IC50 is 13 nM. SEN177 interferes with the interaction between CD47 and SIRRP?, and has anti-tumor activity. SEN177 reduces aggregation and apoptosis caused by HTT mutation in Huntington model, and can be used in the study of neurodegenerative diseases.
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