GENERAL CATALOGUE
Senexin A hydrochloride
HY-15681A · 50 mg
MedChemExpress · Cat: HY-15681A
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Manufacturer product page
medchemexpress.com/senexin-a-hydrochloride.htmlCatalog No: HY-15681A
CAS No: 1780390-76-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
Senexin A hydrochloride is an inhibitor of CDK8/19 IC50: 280 nM, CDK8 and an inhibitor downstream of p21 transcription. It only inhibits p21-induced transcription but does not inhibit other biological effects of p21. Senexin A hydrochloride inhibits CMV-GFP induction as well as the p21 stimulatory activity of the consensus NF-?B-dependent promoters.
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