

HY500140 · 0.1 mL
abm good · Cat: HY500140
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Manufacturer product page
abmgood.com/SensiStain-Anti-CDK4-Antibody-hy500140.html
Description
CDK4 controls cell growth during the cell cycle G1 phase. It is reported that D-type cyclin upregulates Cdk4 activity, whereas binding to the Cdk inhibitor p16 downregulates Cdk4 activity. Cyclin D-CDK4 complexes integrates various mitogenenic and antimitogenic signals and serves as sensitive and specific for atypical lipomatous tumor / well differentiated liposarcoma or dedifferentiated liposarcoma.


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