

AMM81074-100μL · 100μL
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Description
EnkiLife offers the SERPINE1 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Rabbit species and is suitable for IHC,ELISA,FC application. Alternative Names of Immunogen: PAI; PAI1; PAI-1; PLANH1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.







