GENERAL CATALOGUE
SGC-NSP2hel-1
HY-176268 · 50 mg
MedChemExpress · Cat: HY-176268
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Catalog No: HY-176268
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
SGC-NSP2hel-1 RA-0188293 , a chemical probe, is a potent, specific and orally active nsP2 inhibitor. SGC-NSP2hel-1 has broad spectrum activity against multiple alphaviruses of the nsP2 helicase with a CC50 > 250 ?M. SGC-NSP2hel-1 RA-0188293 shows selectivity index > 4000 against human RNA helicases. SGC-NSP2hel-1 reduces virus replication and limited virus-induced pathology by forming a stable complex with nsP2 and ATP in a preclinical small animal model of CHIKV disease.
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