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SGC-SMARCA-BRDVIII
GENERAL CATALOGUE

SGC-SMARCA-BRDVIII

HY-145446 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-145446

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Catalog No: HY-145446
CAS No: 1997319-84-2
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

SGC-SMARCA-BRDVIII, a chemical probe, is a potent and selective inhibitor of SMARCA2/4 and PB1 5 , with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1 2 and PB1 3 , with Kds of 3.7 and 2.0 ?M, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts.

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