GENERAL CATALOGUE
SGC0946
HY-15650 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-15650
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Catalog No: HY-15650
CAS No: 1561178-17-3
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
SGC0946 is a selective DOT1L inhibitor with an IC50 value of 0.3 nM. By inhibiting DOT1L, SGC0946 can induce G1 phase arrest, suppress cell self-renewal and metastatic potential, and induce cell differentiation in cancer cells. SGC0946 can be used in the research of tumors such as leukemia and breast cancer, and also serves as a probe to further investigate the cellular mechanisms of DOT1L in normal and diseased cells.
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