GENERAL CATALOGUE
SGC0946 TFA
HY-15650A · 50 mg
MedChemExpress · Cat: HY-15650A
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Manufacturer product page
medchemexpress.com/sgc0946-tfa.htmlCatalog No: HY-15650A
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
SGC0946 TFA is a selective DOT1L inhibitor with an IC50 value of 0.3 nM. By inhibiting DOT1L, SGC0946 TFA can induce G1 phase arrest, suppress cell self-renewal and metastatic potential, and induce cell differentiation in cancer cells. SGC0946 TFA can be used in the research of tumors such as leukemia and breast cancer, and also serves as a probe to further investigate the cellular mechanisms of DOT1L in normal and diseased cells.
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