GENERAL CATALOGUE
SGC8158
HY-114211 · 1 mg
MedChemExpress · Cat: HY-114211
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medchemexpress.com/sgc8158.htmlCatalog No: HY-114211
Category: Cell Cycle DNA Damage
Pack Size: 1 mg
Brand: MedChemExpress
Description
SGC8158 is an inhibitor of PRMT7 and can be used to study the cellular function of PRMT7. SGC8158 decreases monomethylarginine levels of Hsp70 the best characterized PRMT7 substrate . SGC8158 induces growth inhibition in various cancer cells IC50: 2-9 ?M , as well as multidrug-resistant MDR cancer cells. SGC8158 also enhances Doxorubicin HY-15142A induced DNA damage and Its cytotoxicity.