GENERAL CATALOGUE
SHP099
HY-100388 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100388
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medchemexpress.com/SHP099.html
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Catalog No: HY-100388
CAS No: 1801747-42-1
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
SHP099 is an allosteric SHP2 inhibitor, with IC50s of 0.690, 1.241, 0.416, 1.968, 2.896 AZA14M for SHP2, SHP2D61Y, SHP2E69K, SHP2A72V, . SHP099 inhibits cancer cell growth, such as MV4-11 and TF-1 cell IC50: 0.32 and 1.73 AZA14M . SHP099 inhibits RAS-ERK signaling and inhibits tumor growth.
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