GENERAL CATALOGUE
SHP099 (Standard)
HY-100388R · 5 mg
MedChemExpress · Cat: HY-100388R
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Catalog No: HY-100388R
CAS No: 1801747-42-1
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
SHP099 Standard is the analytical standard of SHP099. This product is intended for research and analytical applications. SHP099 is an allosteric SHP2 inhibitor, with IC50s of 0.690, 1.241, 0.416, 1.968, 2.896 ?M for SHP2, SHP2D61Y, SHP2E69K, SHP2A72V, SHP2E76K. SHP099 inhibits cancer cell growth, such as MV4-11 and TF-1 cell IC50: 0.32 and 1.73 ?M . SHP099 inhibits RAS-ERK signaling and inhibits tumor growth.
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