GENERAL CATALOGUE
SHP2-D26
HY-145162 · 1 mg
MedChemExpress · Cat: HY-145162
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Catalog No: HY-145162
CAS No: 2458219-65-1
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress
Description
SHP2-D26 is a first, potent and effective SHP2 PROTAC degrader. SHP2-D26 induces SHP2 degradation requires binding to VHL-1 and SHP2 proteins. SHP2-D26 is also neddylation- and proteasome-dependent. SHP2-D26 can be used for the study of esophageal cancer and acute myeloid leukemia Pink: SHP2 ligand HY-176797 ; Blue: VHL ligand HY-150803 ; Black: linker .
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