GENERAL CATALOGUE
SHP2-IN-8
HY-144396 · 50 mg
MedChemExpress · Cat: HY-144396
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medchemexpress.com/shp2-in-8.htmlCatalog No: HY-144396
CAS No: 1801692-60-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the ?Tm of 7.01 ?. SHP2-IN-8 induces the apoptosis and inhibits the phosphorylation of AKT in Hela cells.
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