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SI-109
GENERAL CATALOGUE

SI-109

HY-129603 · 1 mg

MedChemExpress · Cat: HY-129603

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medchemexpress.com/si-109.html
Catalog No: HY-129603
CAS No: 2429877-30-3
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress

Description

SI-109 is a potent STAT3 SH2 domain inhibitor Ki=9 nM with antitumor activity. SI-109 effectively inhibits the transcriptional activity of STAT3 IC50=3 ?M . SI-109 and an analog of CRBN ligand lenalidomide have been used to design PROTAC STAT3 degrader SD-36.

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