SIGIRR Rabbit Monoclonal Antibody

Description

EnkiLife offers the SIGIRR Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB application. Alternative Names of Immunogen: TIR8; IL-1R8. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000 Background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.